Investigated event: Influence on tumor cell viability in presence of Sorafenib

Name Value
Compound Capsaicin
Investigated event Influence on tumor cell viability in presence of Sorafenib
Experiment type MTT Assay
Concentration 100.00 µM
Cell line HepG2
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
Capsaicin enhances the antitumor activity of sorafenib in hepatocellular carcinoma cells and mouse xenograft tumors through increased ERK signaling. Acta pharmacologica Sinica Su-Shan Zhang, Yu-Hao Ni, Chen-Ru Zhao, Zhen Qiao, Hong-Xia Yu, Lu-Yao Wang, Jin-Yan Sun, Chen Du, Jia-Hao Zhang, Li-Ying Dong, KeWei Wang, Jian-Jun Gao, 39, 3, None, 2017-11-30, 10.1038/aps.2017.156 DOI: 10.1038/aps.2017.156 PUBMED: 29188798 PMCID: PMC5843835