Investigated event: Influence on STAT3 target gene expression in tumor

Name Value
Compound C188-9
Investigated event Influence on STAT3 target gene expression in tumor
Experiment type RT-PCR
Concentration 50.00 mg/kg
Cell line A549(xenograft)
Organism Mus musculus
Animal model
STAT protein
Other Bcl-xL
Reference
Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands) Katherine M Lewis, Uddalak Bharadwaj, T Kris Eckols, Mikhail Kolosov, Moses M Kasembeli, Colleen Fridley, Ricardo Siller, David J Tweardy, 90, 2, None, 2015-09-15, 10.1016/j.lungcan.2015.09.014 DOI: 10.1016/j.lungcan.2015.09.014 PUBMED: 26410177 PMCID: PMC4619129