Investigated event: Influence on STAT3 target gene expression in tumor
| Name | Value |
|---|---|
| Compound | C188-9 |
| Investigated event | Influence on STAT3 target gene expression in tumor |
| Experiment type | RT-PCR |
| Concentration | 50.00 mg/kg |
| Cell line | A549(xenograft) |
| Organism | Mus musculus |
| Animal model | |
| STAT protein | |
| Other | Bcl-2 |
Reference
Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands) Katherine M Lewis, Uddalak Bharadwaj, T Kris Eckols, Mikhail Kolosov, Moses M Kasembeli, Colleen Fridley, Ricardo Siller, David J Tweardy, 90, 2, None, 2015-09-15, 10.1016/j.lungcan.2015.09.014
DOI: 10.1016/j.lungcan.2015.09.014
PUBMED: 26410177
PMCID: PMC4619129