Investigated event: Measurement of IC50 value JAKs-JH1 truncated kinases
| Name | Value |
|---|---|
| Compound | Brevilin A |
| Investigated event | Measurement of IC50 value JAKs-JH1 truncated kinases |
| Experiment type | Western Blot |
| Concentration | 20.00 µM |
| Cell line | HEK293T (Tyk2-JH1) |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | pTyr705-STAT3 |
| Other |
Reference
Brevilin A, a novel natural product, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells. PloS one Xing Chen, Yuping Du, Jing Nan, Xinxin Zhang, Xiaodong Qin, Yuxin Wang, Jianwen Hou, Qin Wang, Jinbo Yang, 8, 5, None, 2013-05-21, 10.1371/journal.pone.0063697
DOI: 10.1371/journal.pone.0063697
PUBMED: 23704931
PMCID: PMC3660600