Investigated event: Influence on protein activity in presence of IL-6 and CHX

Name Value
Compound Capsaicin
Investigated event Influence on protein activity in presence of IL-6 and CHX
Experiment type Western Blot
Concentration 100.00 µM
Cell line RT4
Organism Rattus norvegicus
Animal model
STAT protein STAT3
Other
Reference
Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress. Biochemical and biophysical research communications Hyun Kyoung Lee, In Ae Seo, Yoon Kyung Shin, Ji Wook Park, Duk Joon Suh, Hwan Tae Park, 382, 2, 2009-05-01, 2009-03-13, 10.1016/j.bbrc.2009.03.046 DOI: 10.1016/j.bbrc.2009.03.046 PUBMED: 19285962 PMCID: 19285962