Investigated event: Antitumor effect
| Name | Value |
|---|---|
| Compound | BP-1-102/ 17o |
| Investigated event | Antitumor effect |
| Experiment type | Tumor size |
| Concentration | 3.00 mg/kg |
| Cell line | MDA-MB-231 (xenograft) |
| Organism | Mus musculus |
| Animal model | |
| STAT protein | |
| Other |
Reference
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109
DOI: 10.1073/pnas.1121606109
PUBMED: 22623533
PMCID: PMC3386073