Investigated event: Influence on gene expression levels in presence of IFNγ
| Name | Value |
|---|---|
| Compound | AG490 |
| Investigated event | Influence on gene expression levels in presence of IFNγ |
| Experiment type | RT-qPCR |
| Concentration | 10.00 µM |
| Cell line | 1774 macrophages |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | iNOS |
Reference
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators of inflammation Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, 2006, 2, None, None, 10.1155/MI/2006/16161
DOI: 10.1155/MI/2006/16161
PUBMED: 16883061
PMCID: PMC1592588