Investigated event: Influence on protein activity in presence of IFNγ
Name | Value |
---|---|
Compound | AG490 |
Investigated event | Influence on protein activity in presence of IFNγ |
Experiment type | Western Blot |
Concentration | 3.00 µM |
Cell line | 1774 macrophages |
Organism | Homo sapiens |
Animal model | |
STAT protein | |
Other | iNOS |
Reference
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators of inflammation Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, 2006, 2, None, None, 10.1155/MI/2006/16161
DOI: 10.1155/MI/2006/16161
PUBMED:
16883061
PMCID: PMC1592588