Investigated event: Inhibition of Jak/STAT signalling
Name | Value |
---|---|
Compound | BBMD3 (berbamine derivative) |
Investigated event | Inhibition of Jak/STAT signalling |
Experiment type | Western Blot |
Concentration | 1.00 µM |
Cell line | A2058 |
Organism | Homo sapiens |
Animal model | |
STAT protein | |
Other | Tyk2 |
Reference
Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells. Molecular oncology Sangkil Nam, Jun Xie, Angela Perkins, Yuelong Ma, Fan Yang, Jun Wu, Yan Wang, Rong-Zhen Xu, Wendong Huang, David A Horne, Richard Jove, 6, 5, None, 2012-06-02, 10.1016/j.molonc.2012.05.002
DOI: 10.1016/j.molonc.2012.05.002
PUBMED:
22717603
PMCID: PMC3439602