Name	Value
Compound	BBMD3 (berbamine derivative)
Investigated event	Inhibition of Jak/STAT signalling
Experiment type	Western Blot
Concentration	0.50 µM
Cell line	A2058
Organism	Homo sapiens
Animal model
STAT protein
Other	p-Tyk2(Tyr1054/1055)

Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells. Molecular oncology Sangkil Nam, Jun Xie, Angela Perkins, Yuelong Ma, Fan Yang, Jun Wu, Yan Wang, Rong-Zhen Xu, Wendong Huang, David A Horne, Richard Jove, 6, 5, None, 2012-06-02, 10.1016/j.molonc.2012.05.002 DOI: 10.1016/j.molonc.2012.05.002 PUBMED: 22717603 PMCID: PMC3439602