Investigated event: Downregulation of IFNγ
| Name | Value |
|---|---|
| Compound | Berbamine |
| Investigated event | Downregulation of IFNγ |
| Experiment type | Western Blot |
| Concentration | 50.00 mg/kg |
| Cell line | Splenocytes |
| Organism | Mus musculus |
| Animal model | c57BL/6 |
| STAT protein | STAT4 |
| Other |
Reference
Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950) Yiping Ren, Limin Lu, Taylor B Guo, Ju Qiu, Yiqing Yang, Ailian Liu, Jingwu Z Zhang, 181, 2, 2008-07-15, None, 10.4049/jimmunol.181.2.1491
DOI: 10.4049/jimmunol.181.2.1491
PUBMED: 18606704
PMCID: 18606704