Investigated event: Influence on protein activity in tumor tissue
| Name | Value |
|---|---|
| Compound | Benzyl isothiocyanate |
| Investigated event | Influence on protein activity in tumor tissue |
| Experiment type | Western Blot |
| Concentration | 20.00 mg/kg |
| Cell line | L3.6pL (xenograft) |
| Organism | Mus musculus |
| Animal model | athymic nu/nu |
| STAT protein | |
| Other | Sp1 |
Reference
Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer. The Journal of biological chemistry Ravi Kasiappan, Indira Jutooru, Keshav Karki, Erik Hedrick, Stephen Safe, 291, 53, 2016-12-30, 2016-11-15, 10.1074/jbc.M116.746339
DOI: 10.1074/jbc.M116.746339
PUBMED: 27875298
PMCID: PMC5207142