Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | AZD1480 |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 1.00 µM |
| Cell line | BMDM |
| Organism | Mus musculus |
| Animal model | c57BL/6 |
| STAT protein | STAT3 |
| Other |
Reference
Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950) Yudong Liu, Andrew T Holdbrooks, Patrizia De Sarno, Amber L Rowse, Lora L Yanagisawa, Braden C McFarland, Laurie E Harrington, Chander Raman, Steffanie Sabbaj, Etty N Benveniste, Hongwei Qin, 192, 1, 2014-01-01, 2013-12-09, 10.4049/jimmunol.1301513
DOI: 10.4049/jimmunol.1301513
PUBMED: 24323580
PMCID: PMC3934829