Investigated event: Influence on protein activity in presence of selumetinib
| Name | Value |
|---|---|
| Compound | AZD1480 |
| Investigated event | Influence on protein activity in presence of selumetinib |
| Experiment type | Western Blot |
| Concentration | 1.00 µM |
| Cell line | PALLSD (xenograft) |
| Organism | |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia. Molecular cancer therapeutics Santi Suryani, Lauryn S Bracken, Richard C Harvey, Keith C S Sia, Hernan Carol, I-Ming Chen, Kathryn Evans, Philipp A Dietrich, Kathryn G Roberts, Raushan T Kurmasheva, Catherine A Billups, Charles G Mullighan, Cheryl L Willman, Mignon L Loh, Stephen P Hunger, Peter J Houghton, Malcolm A Smith, Richard B Lock, 14, 2, None, 2014-12-10, 10.1158/1535-7163.MCT-14-0647
DOI: 10.1158/1535-7163.MCT-14-0647
PUBMED: 25504635
PMCID: PMC4326541