Investigated event: Influence on protein activity

Name Value
Compound AZD1480
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 1.00 µM
Cell line PAKRSL (xenograft)
Organism
Animal model
STAT protein
Other ERK1/2
Reference
Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia. Molecular cancer therapeutics Santi Suryani, Lauryn S Bracken, Richard C Harvey, Keith C S Sia, Hernan Carol, I-Ming Chen, Kathryn Evans, Philipp A Dietrich, Kathryn G Roberts, Raushan T Kurmasheva, Catherine A Billups, Charles G Mullighan, Cheryl L Willman, Mignon L Loh, Stephen P Hunger, Peter J Houghton, Malcolm A Smith, Richard B Lock, 14, 2, None, 2014-12-10, 10.1158/1535-7163.MCT-14-0647 DOI: 10.1158/1535-7163.MCT-14-0647 PUBMED: 25504635 PMCID: PMC4326541