Investigated event: Influence on protein activity

Name Value
Compound AZD1480
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 1.00 µM
Cell line PAKYEP (xenograft)
Organism
Animal model
STAT protein p-STAT5
Other
Reference
Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia. Molecular cancer therapeutics Santi Suryani, Lauryn S Bracken, Richard C Harvey, Keith C S Sia, Hernan Carol, I-Ming Chen, Kathryn Evans, Philipp A Dietrich, Kathryn G Roberts, Raushan T Kurmasheva, Catherine A Billups, Charles G Mullighan, Cheryl L Willman, Mignon L Loh, Stephen P Hunger, Peter J Houghton, Malcolm A Smith, Richard B Lock, 14, 2, None, 2014-12-10, 10.1158/1535-7163.MCT-14-0647 DOI: 10.1158/1535-7163.MCT-14-0647 PUBMED: 25504635 PMCID: PMC4326541