Investigated event: Influence on cell proliferation in tumor tissue

Name Value
Compound SD-36
Investigated event Influence on cell proliferation in tumor tissue
Experiment type Tumor volume
Concentration 50.00 mg/kg
Cell line SUP-M2(xenograft)
Organism Mus musculus
Animal model NOD/SCID
STAT protein
Other
Reference
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer cell Longchuan Bai, Haibin Zhou, Renqi Xu, Yujun Zhao, Krishnapriya Chinnaswamy, Donna McEachern, Jianyong Chen, Chao-Yie Yang, Zhaomin Liu, Mi Wang, Liu Liu, Hui Jiang, Bo Wen, Praveen Kumar, Jennifer L Meagher, Duxin Sun, Jeanne A Stuckey, Shaomeng Wang, 36, 5, 2019-11-11, None, 10.1016/j.ccell.2019.10.002 DOI: 10.1016/j.ccell.2019.10.002 PUBMED: 31715132 PMCID: PMC6880868