Investigated event: Influence on protein activity in tumor tissue
Name | Value |
---|---|
Compound | SD-36 |
Investigated event | Influence on protein activity in tumor tissue |
Experiment type | Western Blot |
Concentration | 25.00 mg/kg |
Cell line | MOLM-16(xenograft) |
Organism | Mus musculus |
Animal model | NOD/SCID |
STAT protein | STAT3 |
Other |
Reference
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer cell Longchuan Bai, Haibin Zhou, Renqi Xu, Yujun Zhao, Krishnapriya Chinnaswamy, Donna McEachern, Jianyong Chen, Chao-Yie Yang, Zhaomin Liu, Mi Wang, Liu Liu, Hui Jiang, Bo Wen, Praveen Kumar, Jennifer L Meagher, Duxin Sun, Jeanne A Stuckey, Shaomeng Wang, 36, 5, 2019-11-11, None, 10.1016/j.ccell.2019.10.002
DOI: 10.1016/j.ccell.2019.10.002
PUBMED:
31715132
PMCID: PMC6880868