Investigated event: Influence on protein activity in tumor tissue
| Name | Value |
|---|---|
| Compound | SD-91 |
| Investigated event | Influence on protein activity in tumor tissue |
| Experiment type | Western Blot |
| Concentration | 50.00 mg/kg |
| Cell line | MOLM-16(xenograft) |
| Organism | Mus musculus |
| Animal model | |
| STAT protein | |
| Other | β-actin |
Reference
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression. ACS medicinal chemistry letters Haibin Zhou, Longchuan Bai, Renqi Xu, Donna McEachern, Krishnapriya Chinnaswamy, Ruiting Li, Bo Wen, Mi Wang, Chao-Yie Yang, Jennifer L Meagher, Duxin Sun, Jeanne A Stuckey, Shaomeng Wang, 12, 6, 2021-06-10, 2021-05-10, 10.1021/acsmedchemlett.1c00155
DOI: 10.1021/acsmedchemlett.1c00155
PUBMED: 34141084
PMCID: PMC8201759
