Investigated event: Influence on protein activity in tumor tissue
Name | Value |
---|---|
Compound | SD-91 |
Investigated event | Influence on protein activity in tumor tissue |
Experiment type | Western Blot |
Concentration | 50.00 mg/kg |
Cell line | MOLM-16(xenograft) |
Organism | Mus musculus |
Animal model | |
STAT protein | |
Other | GAPDH |
Reference
SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression. ACS medicinal chemistry letters Haibin Zhou, Longchuan Bai, Renqi Xu, Donna McEachern, Krishnapriya Chinnaswamy, Ruiting Li, Bo Wen, Mi Wang, Chao-Yie Yang, Jennifer L Meagher, Duxin Sun, Jeanne A Stuckey, Shaomeng Wang, 12, 6, 2021-06-10, 2021-05-10, 10.1021/acsmedchemlett.1c00155
DOI: 10.1021/acsmedchemlett.1c00155
PUBMED:
34141084
PMCID: PMC8201759