Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | TPCA-1 |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 0.10 µM |
| Cell line | 293T |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
TPCA-1 is a direct dual inhibitor of STAT3 and NF-κB and regresses mutant EGFR-associated human non-small cell lung cancers. Molecular cancer therapeutics Jing Nan, Yuping Du, Xing Chen, Qifeng Bai, Yuxin Wang, Xinxin Zhang, Ning Zhu, Jing Zhang, Jianwen Hou, Qin Wang, Jinbo Yang, 13, 3, None, 2014-01-08, 10.1158/1535-7163.MCT-13-0464
DOI: 10.1158/1535-7163.MCT-13-0464
PUBMED: 24401319
PMCID: 24401319