Investigated event: Influence on transcriptional activity in presence of GH
| Name | Value |
|---|---|
| Compound | Simvastatin |
| Investigated event | Influence on transcriptional activity in presence of GH |
| Experiment type | RT-qPCR |
| Concentration | 20.00 µM |
| Cell line | UMR-106 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | SOCS-3 |
Reference
Simvastatin impairs growth hormone-activated signal transducer and activator of transcription (STAT) signaling pathway in UMR-106 osteosarcoma cells. PloS one María Claudia Sandoval-Usme, Adriana Umaña-Pérez, Borja Guerra, Octavio Hernández-Perera, Orlando Hernández-Perera, José Manuel García-Castellano, Leandro Fernández-Pérez, Myriam Sánchez-Gómez, 9, 1, None, 2014-01-29, 10.1371/journal.pone.0087769
DOI: 10.1371/journal.pone.0087769
PUBMED: 24489959
PMCID: PMC3906206