Investigated event: Influence on protein activity (10h) in presence of GH

Name Value
Compound Simvastatin
Investigated event Influence on protein activity (10h) in presence of GH
Experiment type Western Blot
Concentration 7.00 µM
Cell line UMR-106
Organism Homo sapiens
Animal model
STAT protein p-STAT5(S726/731)
Other
Reference
Simvastatin impairs growth hormone-activated signal transducer and activator of transcription (STAT) signaling pathway in UMR-106 osteosarcoma cells. PloS one María Claudia Sandoval-Usme, Adriana Umaña-Pérez, Borja Guerra, Octavio Hernández-Perera, Orlando Hernández-Perera, José Manuel García-Castellano, Leandro Fernández-Pérez, Myriam Sánchez-Gómez, 9, 1, None, 2014-01-29, 10.1371/journal.pone.0087769 DOI: 10.1371/journal.pone.0087769 PUBMED: 24489959 PMCID: PMC3906206