Investigated event: Influence on cytokine production

Name Value
Compound YM-341619
Investigated event Influence on cytokine production
Experiment type ELISA
Concentration 1.00 µM
Cell line Spleen T cells
Organism Mus musculus
Animal model c57BL/6
STAT protein
Other IFNγ
Reference
Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors. Bioorganic & medicinal chemistry Shinya Nagashima, Hiroshi Nagata, Masahiro Iwata, Masaki Yokota, Hiroyuki Moritomo, Masaya Orita, Sadao Kuromitsu, Akiko Koakutsu, Keiko Ohga, Makoto Takeuchi, Mitsuaki Ohta, Shin-ichi Tsukamoto, 16, 13, 2008-07-01, 2008-05-17, 10.1016/j.bmc.2008.05.031 DOI: 10.1016/j.bmc.2008.05.031 PUBMED: 18534856 PMCID: 18534856