Investigated event: Influence on cytokine production
| Name | Value |
|---|---|
| Compound | YM-341619 |
| Investigated event | Influence on cytokine production |
| Experiment type | ELISA |
| Concentration | 0.10 µM |
| Cell line | Spleen T cells |
| Organism | Mus musculus |
| Animal model | c57BL/6 |
| STAT protein | |
| Other | IFNγ |
Reference
Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors. Bioorganic & medicinal chemistry Shinya Nagashima, Hiroshi Nagata, Masahiro Iwata, Masaki Yokota, Hiroyuki Moritomo, Masaya Orita, Sadao Kuromitsu, Akiko Koakutsu, Keiko Ohga, Makoto Takeuchi, Mitsuaki Ohta, Shin-ichi Tsukamoto, 16, 13, 2008-07-01, 2008-05-17, 10.1016/j.bmc.2008.05.031
DOI: 10.1016/j.bmc.2008.05.031
PUBMED: 18534856
PMCID: 18534856