Investigated event: Influence on tumor growth
Name | Value |
---|---|
Compound | Withacnistin |
Investigated event | Influence on tumor growth |
Experiment type | Tumor volume |
Concentration | 20.00 mg/kg |
Cell line | MDA-MB-468(xenograft) |
Organism | Mus musculus |
Animal model | ErbB2 |
STAT protein | |
Other |
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349
DOI: 10.1038/bjc.2014.349
PUBMED:
24983364
PMCID: PMC4150266