Investigated event: Influence on protein transcriptiona activity
Name | Value |
---|---|
Compound | Withacnistin |
Investigated event | Influence on protein transcriptiona activity |
Experiment type | Luciferse activity |
Concentration | 10.00 µM |
Cell line | MDA-MB-468 |
Organism | Homo sapiens |
Animal model | |
STAT protein | |
Other | pLuc-TKS3 |
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349
DOI: 10.1038/bjc.2014.349
PUBMED:
24983364
PMCID: PMC4150266