Investigated event: Influence on protein activity in presence of EGF

Name Value
Compound Withacnistin
Investigated event Influence on protein activity in presence of EGF
Experiment type Co-immunoprecipitation
Concentration 10.00 µM
Cell line U-266
Organism Homo sapiens
Animal model
STAT protein
Other GP130
Reference
Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumours. British journal of cancer X Zhang, M A Blaskovich, K D Forinash, S M Sebti, 111, 5, 2014-08-26, 2014-07-01, 10.1038/bjc.2014.349 DOI: 10.1038/bjc.2014.349 PUBMED: 24983364 PMCID: PMC4150266