Investigated event: Influence on trancriptional activity

Name Value
Compound SF-1-088
Investigated event Influence on trancriptional activity
Experiment type RT-PCR
Concentration 40.00 µM
Cell line K562
Organism Homo sapiens
Animal model
STAT protein
Other Cyclin D2
Reference
Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity. Journal of medicinal chemistry Brent D G Page, Haytham Khoury, Rob C Laister, Steven Fletcher, Megan Vellozo, Alessia Manzoli, Peibin Yue, James Turkson, Mark D Minden, Patrick T Gunning, 55, 3, 2012-02-09, 2012-01-13, 10.1021/jm200720n DOI: 10.1021/jm200720n PUBMED: 22148584 PMCID: 22148584