Investigated event: Influence on protein activity

Name Value
Compound SC-1.SC-49
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 7.50 µM
Cell line U937
Organism Homo sapiens
Animal model
STAT protein
Other Cyclin D1
Reference
Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody. British journal of pharmacology Kuen-Feng Chen, Hui-Ling Chen, Chung-Wai Shiau, Chun-Yu Liu, Pei-Yi Chu, Wei-Tien Tai, Kimihisa Ichikawa, Pei-Jer Chen, Ann-Lii Cheng, 168, 3, None, None, 10.1111/j.1476-5381.2012.02212.x DOI: 10.1111/j.1476-5381.2012.02212.x PUBMED: 22978563 PMCID: PMC3579286