Investigated event: Influence on protein activity

Name Value
Compound SC-1.SC-49
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 2.50 µM
Cell line Hep3B
Organism Homo sapiens
Animal model
STAT protein p-STAT3
Other
Reference
Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody. British journal of pharmacology Kuen-Feng Chen, Hui-Ling Chen, Chung-Wai Shiau, Chun-Yu Liu, Pei-Yi Chu, Wei-Tien Tai, Kimihisa Ichikawa, Pei-Jer Chen, Ann-Lii Cheng, 168, 3, None, None, 10.1111/j.1476-5381.2012.02212.x DOI: 10.1111/j.1476-5381.2012.02212.x PUBMED: 22978563 PMCID: PMC3579286