Investigated event: Influence on protein activity
| Name | Value |
|---|---|
| Compound | SC-1.SC-49 |
| Investigated event | Influence on protein activity |
| Experiment type | Western Blot |
| Concentration | 2.50 µM |
| Cell line | Hep3B |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 |
| Other |
Reference
Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody. British journal of pharmacology Kuen-Feng Chen, Hui-Ling Chen, Chung-Wai Shiau, Chun-Yu Liu, Pei-Yi Chu, Wei-Tien Tai, Kimihisa Ichikawa, Pei-Jer Chen, Ann-Lii Cheng, 168, 3, None, None, 10.1111/j.1476-5381.2012.02212.x
DOI: 10.1111/j.1476-5381.2012.02212.x
PUBMED: 22978563
PMCID: PMC3579286