Investigated event: Influence on atherosclerosis progression

Name Value
Compound Pravastatin
Investigated event Influence on atherosclerosis progression
Experiment type Western Blot
Concentration 80.00 mg/kg
Cell line thoracoabdominal aortas
Organism Mus musculus
Animal model ApoE-/-
STAT protein
Other β-actin
Reference
Pravastatin prevents aortic atherosclerosis via modulation of signal transduction and activation of transcription 3 (STAT3) to attenuate interleukin-6 (IL-6) action in ApoE knockout mice. International journal of molecular sciences Xiaoxu Zhou, Dan Li, Wei Yan, Weimin Li, 9, 11, None, 2008-11-14, 10.3390/ijms9112253 DOI: 10.3390/ijms9112253 PUBMED: 19330073 PMCID: PMC2635628