Investigated event: Influence on atherosclerosis progression
| Name | Value |
|---|---|
| Compound | Pravastatin |
| Investigated event | Influence on atherosclerosis progression |
| Experiment type | TC levels assesment |
| Concentration | 80.00 mg/kg |
| Cell line | serum |
| Organism | Mus musculus |
| Animal model | ApoE-/- |
| STAT protein | |
| Other |
Reference
Pravastatin prevents aortic atherosclerosis via modulation of signal transduction and activation of transcription 3 (STAT3) to attenuate interleukin-6 (IL-6) action in ApoE knockout mice. International journal of molecular sciences Xiaoxu Zhou, Dan Li, Wei Yan, Weimin Li, 9, 11, None, 2008-11-14, 10.3390/ijms9112253
DOI: 10.3390/ijms9112253
PUBMED: 19330073
PMCID: PMC2635628