Investigated event: Influence on tumor growth
Name | Value |
---|---|
Compound | inS3-54A18 |
Investigated event | Influence on tumor growth |
Experiment type | Body weight |
Concentration | 200.00 mg/kg |
Cell line | A549 (xenograft) |
Organism | Mus musculus |
Animal model | NOD/SCID |
STAT protein | |
Other |
Reference
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene W Huang, Z Dong, Y Chen, F Wang, C J Wang, H Peng, Y He, G Hangoc, K Pollok, G Sandusky, X-Y Fu, H E Broxmeyer, Z-Y Zhang, J-Y Liu, J-T Zhang, 35, 6, 2016-02-11, 2015-06-15, 10.1038/onc.2015.215
DOI: 10.1038/onc.2015.215
PUBMED:
26073084
PMCID: 26073084