Investigated event: Influence on protein activity

Name Value
Compound inS3-54A18
Investigated event Influence on protein activity
Experiment type Chromatin immunoprecipitation assay
Concentration 10.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other Histone (soluble nuclear)
Reference
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene W Huang, Z Dong, Y Chen, F Wang, C J Wang, H Peng, Y He, G Hangoc, K Pollok, G Sandusky, X-Y Fu, H E Broxmeyer, Z-Y Zhang, J-Y Liu, J-T Zhang, 35, 6, 2016-02-11, 2015-06-15, 10.1038/onc.2015.215 DOI: 10.1038/onc.2015.215 PUBMED: 26073084 PMCID: 26073084