Investigated event: Influence on protein binding to DNA
| Name | Value |
|---|---|
| Compound | inS3-54A18 |
| Investigated event | Influence on protein binding to DNA |
| Experiment type | EMSA |
| Concentration | 13.00 µM |
| Cell line | H1299 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene W Huang, Z Dong, Y Chen, F Wang, C J Wang, H Peng, Y He, G Hangoc, K Pollok, G Sandusky, X-Y Fu, H E Broxmeyer, Z-Y Zhang, J-Y Liu, J-T Zhang, 35, 6, 2016-02-11, 2015-06-15, 10.1038/onc.2015.215
DOI: 10.1038/onc.2015.215
PUBMED: 26073084
PMCID: 26073084
