Investigated event: Influence on protein activity

Name Value
Compound Dasatinib
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 100.00 nM
Cell line BaF3 JAK2 V617F
Organism Homo sapiens
Animal model
STAT protein
Other β-actin
Reference
Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm. British journal of haematology Santiago Barrio, Miguel Gallardo, Alicia Arenas, Rosa Ayala, Inmaculada Rapado, Daniel Rueda, Ana Jimenez, Enriqueta Albizua, Carmen Burgaleta, Florinda Gilsanz, Joaquin Martinez-Lopez, 161, 5, None, 2013-04-05, 10.1111/bjh.12308 DOI: 10.1111/bjh.12308 PUBMED: 23560534 PMCID: 23560534