Investigated event: Influence on protein activity
| Name | Value |
|---|---|
| Compound | Dasatinib |
| Investigated event | Influence on protein activity |
| Experiment type | Western Blot |
| Concentration | 10.00 nM |
| Cell line | BaF3 JAK2 V617F |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | p-ERK |
Reference
Inhibition of related JAK/STAT pathways with molecular targeted drugs shows strong synergy with ruxolitinib in chronic myeloproliferative neoplasm. British journal of haematology Santiago Barrio, Miguel Gallardo, Alicia Arenas, Rosa Ayala, Inmaculada Rapado, Daniel Rueda, Ana Jimenez, Enriqueta Albizua, Carmen Burgaleta, Florinda Gilsanz, Joaquin Martinez-Lopez, 161, 5, None, 2013-04-05, 10.1111/bjh.12308
DOI: 10.1111/bjh.12308
PUBMED: 23560534
PMCID: 23560534