Investigated event: Influence on eosinophils accumulation in BALF
| Name | Value |
|---|---|
| Compound | AS1810722 |
| Investigated event | Influence on eosinophils accumulation in BALF |
| Experiment type | Differential cell count |
| Concentration | 0.30 mg/kg |
| Cell line | eosinophil |
| Organism | Mus musculus |
| Animal model | BALB/c |
| STAT protein | |
| Other |
Reference
Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors. Bioorganic & medicinal chemistry Shinya Nagashima, Takeshi Hondo, Hiroshi Nagata, Takashi Ogiyama, Jun Maeda, Hiroaki Hoshii, Toru Kontani, Sadao Kuromitsu, Keiko Ohga, Masaya Orita, Kazuki Ohno, Ayako Moritomo, Koichi Shiozuka, Masako Furutani, Makoto Takeuchi, Mitsuaki Ohta, Shin-ichi Tsukamoto, 17, 19, 2009-10-01, 2009-08-15, 10.1016/j.bmc.2009.08.021
DOI: 10.1016/j.bmc.2009.08.021
PUBMED: 19747833
PMCID: 19747833