Investigated event: Influence on cell apoposis in presence of Bortezomib
| Name | Value |
|---|---|
| Compound | Resveratrol |
| Investigated event | Influence on cell apoposis in presence of Bortezomib |
| Experiment type | Flow cytometry- annexin V binding and propidium iodide staining |
| Concentration | 25.00 µM |
| Cell line | Enriched CD138+ |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other |
Reference
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood Anjana Bhardwaj, Gautam Sethi, Saroj Vadhan-Raj, Carlos Bueso-Ramos, Yasunari Takada, Upasna Gaur, Asha S Nair, Shishir Shishodia, Bharat B Aggarwal, 109, 6, 2007-03-15, 2006-12-12, 10.1182/blood-2006-02-003988
DOI: 10.1182/blood-2006-02-003988
PUBMED: 17164350
PMCID: 17164350