Investigated event: Influence on STAT protein activity in presence of Thalidomide

Name Value
Compound Resveratrol
Investigated event Influence on STAT protein activity in presence of Thalidomide
Experiment type EMSA
Concentration 50.00 µM
Cell line RPMI 8226
Organism Homo sapiens
Animal model
STAT protein
Other NF-κB
Reference
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood Anjana Bhardwaj, Gautam Sethi, Saroj Vadhan-Raj, Carlos Bueso-Ramos, Yasunari Takada, Upasna Gaur, Asha S Nair, Shishir Shishodia, Bharat B Aggarwal, 109, 6, 2007-03-15, 2006-12-12, 10.1182/blood-2006-02-003988 DOI: 10.1182/blood-2006-02-003988 PUBMED: 17164350 PMCID: 17164350