Investigated event: Influence on protein activity in tumor tissue
| Name | Value |
|---|---|
| Compound | AZD1480 |
| Investigated event | Influence on protein activity in tumor tissue |
| Experiment type | Western Blot |
| Concentration | 30.00 mg/kg |
| Cell line | Rh18 (xenograft) |
| Organism | Mus musculus |
| Animal model | athymic nude mice |
| STAT protein | |
| Other | Bcl-2 |
Reference
Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo. Oncotarget Shuang Yan, Zhijie Li, Carol J Thiele, 4, 3, None, None, 10.18632/oncotarget.930
DOI: 10.18632/oncotarget.930
PUBMED: 23531921
PMCID: PMC3717306