Investigated event:
| Name | Value |
|---|---|
| Compound | Atiprimod |
| Investigated event | |
| Experiment type | DNA Fragmentation Assay |
| Concentration | 1.25 µM |
| Cell line | HepG2.2.15 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | Caspase-3/7 |
Reference
Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Molecular cancer therapeutics Sweeta R Choudhari, Muhammad A Khan, Genesis Harris, Donald Picker, Gary S Jacob, Timothy Block, Kunwar Shailubhai, 6, 1, None, None, 10.1158/1535-7163.MCT-06-0561
DOI: 10.1158/1535-7163.MCT-06-0561
PUBMED: 17237271
PMCID: 17237271