Investigated event: Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib
| Name | Value |
|---|---|
| Compound | Arsenic trioxide |
| Investigated event | Influence on JAK/STAT target mRNA expression level in presence of ruxolitninib |
| Experiment type | RT-qPCR |
| Concentration | 2.00 µM |
| Cell line | KG-1 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | BCL2 |
Reference
Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen species. European journal of pharmacology Yashar Mesbahi, Ali Zekri, Seyed H Ghaffari, Parvaneh Sadat Tabatabaie, Shahin Ahmadian, Ardeshir Ghavamzadeh, 834, None, 2018-09-05, 2018-07-19, 10.1016/j.ejphar.2018.07.010
DOI: 10.1016/j.ejphar.2018.07.010
PUBMED: 30012499
PMCID: 30012499