Investigated event: Influence on cell proliferation in tumor tissue
| Name | Value |
|---|---|
| Compound | Arsenic trioxide |
| Investigated event | Influence on cell proliferation in tumor tissue |
| Experiment type | Body weight |
| Concentration | 2.00 mg/kg |
| Cell line | AGS (xenograft0 |
| Organism | Mus musculus |
| Animal model | BALB/c athymin nude mice |
| STAT protein | |
| Other |
Reference
Arsenic trioxide attenuates STAT-3 activity and epithelial-mesenchymal transition through induction of SHP-1 in gastric cancer cells. BMC cancer Sung Ho Kim, Hyo Soon Yoo, Moon Kyung Joo, Taehyun Kim, Jong-Jae Park, Beom Jae Lee, Hoon Jai Chun, Sang Woo Lee, Young-Tae Bak, 18, 1, 2018-02-06, 2018-02-06, 10.1186/s12885-018-4071-9
DOI: 10.1186/s12885-018-4071-9
PUBMED: 29409467
PMCID: PMC5801683