Investigated event: Influence on protein activity in presence of doxorubicin

Name Value
Compound Andrographolide
Investigated event Influence on protein activity in presence of doxorubicin
Experiment type Western Blot
Concentration 15.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other Bcl-xL
Reference
Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin. Biochemical pharmacology Jing Zhou, Choon-Nam Ong, Gang-Min Hur, Han-Ming Shen, 79, 9, 2010-05-01, 2009-12-21, 10.1016/j.bcp.2009.12.014 DOI: 10.1016/j.bcp.2009.12.014 PUBMED: 20026083 PMCID: 20026083