Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | Andrographolide |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 15.00 µM |
| Cell line | HCT116 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 (Tyr705) |
| Other |
Reference
Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin. Biochemical pharmacology Jing Zhou, Choon-Nam Ong, Gang-Min Hur, Han-Ming Shen, 79, 9, 2010-05-01, 2009-12-21, 10.1016/j.bcp.2009.12.014
DOI: 10.1016/j.bcp.2009.12.014
PUBMED: 20026083
PMCID: 20026083