Investigated event: Influence on mRNA expression level in presence of LPS
| Name | Value |
|---|---|
| Compound | Andrographolide |
| Investigated event | Influence on mRNA expression level in presence of LPS |
| Experiment type | RT-qPCR |
| Concentration | 2.00 µM |
| Cell line | RAW264.7 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | SOCS3 |
Reference
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. Journal of ethnopharmacology Ko-Chen Lee, Hen-Hong Chang, Ying-Hui Chung, Tzung-Yan Lee, 135, 3, 2011-06-01, 2011-04-08, 10.1016/j.jep.2011.03.068
DOI: 10.1016/j.jep.2011.03.068
PUBMED: 21497192
PMCID: 21497192