Investigated event: Influence on protein activity in presence of LPS
| Name | Value |
|---|---|
| Compound | Andrographolide |
| Investigated event | Influence on protein activity in presence of LPS |
| Experiment type | Western Blot |
| Concentration | 50.00 µM |
| Cell line | RAW264.7 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 (Tyr705) |
| Other |
Reference
Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264.7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway. Journal of ethnopharmacology Ko-Chen Lee, Hen-Hong Chang, Ying-Hui Chung, Tzung-Yan Lee, 135, 3, 2011-06-01, 2011-04-08, 10.1016/j.jep.2011.03.068
DOI: 10.1016/j.jep.2011.03.068
PUBMED: 21497192
PMCID: 21497192